Advertising Disclosure
The Top 3 GLP-1 Supplements for Appetite Control & Weight Support in 2025
The Top 3 GLP-1 Supplements for Appetite Control & Weight Support in 2025
Reviewed by:
Abby Milton R.N.D
September 12, 2025
Written and Edited By SA EDITORIAL TEAM
Trim Path
- Most Clinically Studied Ingredients
- Helps manages healthy weight levels
- Helps regulate appetite
EUNOIA™ Cortisol Reduction Capsules
- Most Clinically Studied Ingredients
- Helps manages healthy weight levels
- Naturally improves energy levels
It’s no secret that constant cravings, stalled weight loss, and energy crashes are some of the most frustrating wellness challenges today. Many people feel overwhelmed by “food noise,” stubborn fat that refuses to budge, or the guilt of failed diets and worry these struggles will only continue to build. It’s no mystery why GLP-1 supplements have become so popular with those searching for a natural way to finally feel in control. But not all GLP-1 supplements are created equal. That’s why we tested some of the most talked-about formulas and narrowed it down to the top three that truly deliver results.
Why Most GLP-1 Supplements Disappoint
The supplement market is crowded, but unfortunately, many products don’t live up to their promises. Too often we found formulas that relied only on basic probiotics without addressing the deeper hormonal drivers of appetite. Others were underdosed, filled with cheap fillers, or priced far above what they were worth. For customers, that means wasted money and more frustration on top of an already exhausting journey.
The good news: not everything we tested fell short. A few formulas combined thoughtful ingredient science with real-world effectiveness and fair value. These are the three that stood out
OUR TOP 3 CHOICES
Best Overall
Trim Path
4.8 / 5.0
Best for:
- Anyone struggling with constant cravings and food noise
- Those looking for natural weight support without stimulants
- People who want maximum results for the best value
Best Overall Performance & Value
| Format | Easy-to-swallow vegan capsules |
|---|---|
| Key Ingredients | Ceylon Cinnamon Extract, Chromium Picolinate, Vitamin B Complex, Enhanced Berberine HCl, Akkermansia muciniphila, Dual-Phase Release Capsule |
| Use | Adults take 1 capsule daily with food |
| Regular Price | $36 per bottle (~$1.20 per capsule) |
Where It Shines
Trim Path leads because it takes a complete approach. While most brands focus only on probiotics, Trim Path blends botanicals, minerals, vitamins, and next-generation probiotics that work together to regulate appetite and support healthy metabolism. The dual-phase capsule design also ensures ingredients are released at the right time for the best effect.
What’s Inside:
-
Ceylon Cinnamon Extract (500mg):
Helps regulate blood sugar and improve insulin sensitivity. -
Chromium Picolinate (200mcg):
Promotes stable blood sugar, reducing energy dips and cravings. -
Vitamin B Complex:
Supports metabolism and steady cellular energy. -
Enhanced Berberine HCl (1000mg):
Research-backed for blood sugar balance and weight management -
Akkermansia muciniphila (30B CFU):
A protected probiotic that directly stimulates GLP-1, the body’s natural satiety hormone. -
Dual-Phase Release Capsule:
Maximizes absorption and ensures sustained results.
PROS:
- Comprehensive, multi-action formula (beyond probiotics)
- Excellent value at $1.20 per capsule
- Dual-phase release for better absorption
- Balances appetite, metabolism, and energy
CONS:
- Available online only
- Popularity can lead to frequent sellouts
Our Take:
Trim Path offers the best mix of science, results, and value. It’s affordable, thoughtfully designed, and addresses appetite, cravings, and metabolism from multiple angles.
Top Choice
EUNOIA™ Cortisol Reduction Capsules
4.8 / 5.0
Best for: Balancing cortisol levels and reducing stress naturally. Ideal for those dealing with brain fog, stress eating, burnout, and difficulty relaxing.
Best Overall Performance & Value
| Format | Easy-to-swallow vegan capsules |
|---|---|
| Key Ingredients | Cordyceps Sinesis Powder (Mycelium), Reishi Mushroom Extract, Shiitake Mushroom Extract, and Lions Mane |
| Use | 2 capsules daily for calm, clarity, and hormonal balance |
| Regular Price | $35.90 for 60 capsules (~ $0.59 per capsule) |
Eunoia blends 10 adaptogenic super mushrooms to help your body manage daily stress naturally and from within. Together, they support balanced cortisol levels, increased energy, better sleep, and lower anxiety. On top of that, it helps reduce bloating and the puffy “cortisol face” look. So you’ll feel and look better.
“It’s not just that I feel calmer, I feel clearer. I’m sleeping better, my stomach’s not as puffy, and I’m not snapping at my kids anymore.”
WHY IS IT THE BEST:
- Naturally fights high cortisol levels
- Helps deal with daily stress
- Provides natural energy boost
- Promotes focus and mental clarity
PROS:
- Naturally sourced Ingredients
- Targets stress, fatigue, bloating, and sleep
- No melatonin or stimulants
- Vegan, sugar-free, gentle on sensitive stomachs
- Results you can feel: Less stress, clearer skin, reduced "cortisol face", and flattened belly
- Best price per capsule ($0.66)
CONS:
- Goes out of stock frequently due to high demand
- Only available online
- Requires consistent daily use
Premium Pick
Pendulum GLP-1 Probiotic
4.8 / 5.0
Best for:
- Those willing to pay more for a premium Amazon brand
- People familiar with probiotic-based GLP-1 support
- Buyers who prefer a recognizable label
BEST OVERALL PERFORMANCE AND VALUE
| Format | Capsules |
|---|---|
| Key Ingredients | Akkermansia muciniphila |
| Use | Adults take 1 capsule daily with food |
| Price | $2.40 per capsule (highest of the three) |
Where It Shines
This brand focuses primarily on probiotics to support gut health, which can play a role in appetite control. It’s a trusted option on Amazon with consistent positive reviews and wide availability.
PROS:
- Long-lasting calm (8 hours)
- Clean, high-tech delivery
- Premium mood support
CONS:
- Highest price per capsule ($1.99)
- Doesn’t target physical stress symptoms like bloating, cravings, or sleep
Our Take:
A dependable option if you want a probiotic-first approach, but much pricier than Trim Path and lacking the broader ingredient support.
Alternative Option
Pendulum Akkermansia Probiotic
4.8 / 5.0
Best for:
- Shoppers looking for a straightforward probiotic option
- Those who prefer a mid-range Amazon choice
- People okay with paying more for simplicity
BEST OVERALL PERFORMANCE AND VALUE
| Format | Capsules |
|---|---|
| Key Ingredients | Akkermansia muciniphila |
| Use | Adults take 1 capsule daily with food |
| Price | $2.00 per capsule |
Where It Shines:
This product offers a clean probiotic formula that supports gut health and digestion. It’s well-reviewed and widely available, making it an easy option to add to a wellness routine.
PROS:
- Great for brain fog and mental burnout
- Clean, pharmaceutical-grade reputation
- Slightly more affordable than Ritual per capsule
CONS:
- Still a higher price ($1.05 per capsule)
- Doesn’t address physical stress symptoms like sleep or digestion
Our Take:
A decent mid-tier alternative, but not as effective or cost-efficient as Trim Path.
Final Thoughts
When it comes to appetite control and sustainable weight support, Trim Path is the clear #1 choice. At just $36 per bottle ($1.20 per capsule), it outperforms the competition in both results and value, thanks to its combination of probiotics, botanicals, and minerals that target cravings, metabolism, and energy together.
If you’re ready to finally quiet the food noise, stabilize your energy, and see real, lasting progress Trim Path is the one to start with.
